Based on the spy novel of the same name by Jacques Futrelle.
The setting of the story is Mexico. Violent bandit and cattle rustler Pancho, his rude henchman Santas and a group of raiders have sworn to drive the settlers out of the Border country. In the conflict that follows, Harry's father Bill is mortally wounded, and Pancho's hands are crushed, supposedly by the ranchers, though the act is actually committed by his traitorous and vengeful lieutenant Santas and his equally slimy compatriot Rodriguez, whom Pancho has offended by denying one his daughter's hand, and the other permission to pursue Rancher's daughter Ruth Chadwick. Pancho swears bitter revenge on the Burrels and the two factions resolve to destroy each other.
Funloving Pearl White, working in a garment sweatshop, gets her big chance when she "opens" for a delayed Shakespeare play...with a comic vaudeville performance. Her brief stage career leads her into those "horrible" moving pictures, where she comes to love the chaotic world of silent movies, becoming queen of the serials. But the consequences of movie stardom may be more than her leading man can take